PAEA Surgery End Of Rotation (EOR) Practice Exam

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Why is porcelain gallbladder concerning?

It has a strong association with pancreatitis.
It is linked to gallbladder cancer.
It is non-removable surgically.
It causes chronic renal failure.

The correct answer is: It is linked to gallbladder cancer.

A porcelain gallbladder is concerning primarily because it is associated with an increased risk of gallbladder cancer. This rare condition is characterized by calcification of the gallbladder wall, often visible on imaging studies as a porcelain-like appearance. The calcification may be a response to chronic inflammation, which can lead to dysplastic changes in the gallbladder epithelium over time, creating a fertile ground for the development of cancer. The prevalence of gallbladder cancer is significantly higher in individuals with a porcelain gallbladder, prompting many clinicians to recommend surgical intervention (cholecystectomy) when this condition is identified, even in the absence of symptoms. Early detection and removal are crucial to reduce the risk of developing malignancy. While other conditions listed may have their own concerns, they do not directly tie to the increases in malignancy associated with a porcelain gallbladder. Thus, understanding the risks associated with this anatomical anomaly is critical for appropriate management and monitoring of patients diagnosed with it.