PAEA Surgery End Of Rotation (EOR) Practice Exam

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Guidelines for the use of antibiotics recommend administration within what timeframe of surgery?

30 minutes
1 hour
2 hours
4 hours

The correct answer is: 1 hour

The guideline for the administration of antibiotics prior to surgery is to give them within one hour before the incision is made. This is particularly crucial in preventing surgical site infections, as timely antibiotic prophylaxis ensures that the drug reaches effective tissue concentrations at the time of the surgical procedure. Administering the antibiotic too early could lead to subtherapeutic levels by the time the surgery begins, while delaying it beyond one hour may increase the risk of infection. In many clinical scenarios, especially for certain high-risk surgical procedures, the benefits of preoperative antibiotics are maximized when they are given just prior to surgery, aligning with the body’s pharmacokinetics to provide optimal protection against pathogens. This emphasizes the importance of adherence to this guideline in surgical practice to improve patient outcomes.