PAEA Surgery End Of Rotation (EOR) Practice Exam

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What is the common age range for onset of esophageal cancer?

  1. 20s to 30s

  2. 40s to 50s

  3. 60s and older

  4. 70s and older

The correct answer is: 60s and older

Esophageal cancer most commonly occurs in individuals in their 60s and older. This age group is particularly affected due to the cumulative risks associated with factors that contribute to esophageal cancer, such as chronic gastroesophageal reflux disease (GERD), smoking, alcohol consumption, and dietary factors. As biological processes age, the likelihood of cellular mutations and the development of malignancies increases, making older adults more susceptible to conditions like esophageal cancer. The risk does begin to rise significantly in the decades leading up to this common onset age, but the majority of cases are indeed diagnosed in individuals aged 60 and above. This demographic perspective aligns with the epidemiological data that illustrates an increase in incidence rates as age progresses, emphasizing the importance of age as a significant factor in the onset of this type of cancer.